List of the Main Foreign Patents

Peptides Bioregulators

№

Patent №

Title

Authors

Country,
year of issue

1.

CH № 659586 А5

Arzneimittel aus dem Thymus und Verfahren zu dessen Herstellung.
(Pharmaceutical substance from thymus gland and method for producing the same)

Morozov V.G.,
Khavinson V.Kh.

Switzerland and Liechtenstein
13.02.1987

2.

DE, № 3421789 С2

Arzneimittel auf der Basis einer Thymusfraktion und Verfahren zu dessen Herstellung.
(Thymus-gland substance and method for producing the same)

Morozov V.G.,
Khavinson V.Kh.

Germany, 
06.10.1988

3.

Fr, № 2583982

Produit medicamenteux obtenu a partir du thymus et son procede d’obtention.
(Thymus-gland substance and method for producing the same)

Morozov V.G.,
Khavinson V.Kh.

France, 
24.02.1989

4.

JP, № 1625201

Process for Production of Thymus Gland Preparation.

Morozov V.G.,
Khavinson V.Kh.

Japan, 
18.11.1991

5.

US, № 5,070,076

Thymus-Gland preparation and method for producing same.

Morozov V.G.,
Khavinson V.Kh.

USA, 
03.12.1991

6.

AU, № 616236

Pharmaceutical preparation for treating immunodeficiency conditions.

Yakovlev G.M.,
Morozov V.G.,
Khavinson V.Kh.
Deigin V.I.,
Korotkov A.M.

Australia, 
03.03.1992

7.

EP, № 0346501

Arzneimittelzubereitung zur behandlung des immunmangels.
(Pharmaceutical preparation for therapy of immunodeficit states)

Yakovlev G.M.,
Morozov V.G.,
Khavinson V.Kh.
Deigin V.I.,
Korotkov A.M.

European patent,
29.07.1992

8.

CА, № 1,330,300

Pharmaceutical preparation for therapy of immunodeficit states.

Yakovlev G.M.,
Morozov V.G.,
Khavinson V.Kh.
Deigin V.I.,
Korotkov A.M.

Canada, 
21.06.1994

9.

US, № 5,538,951

Pharmaceutical preparation for the therapy of immune deficiency conditions.

Morozov V.G.,
Khavinson V.Kh.

USA, 
23.07.1996

10.

US № 5,728,680

Methods for normalizing numbers of lymphocytes.

Morozov V.G.,
Khavinson V.Kh.

USA, 
17.03.1998

11.

US № 5,767,087

Pharmaceutical preparation for the therapy of immune deficiency conditions.

Morozov V.G.,
Khavinson V.Kh.

USA, 
16.06.1998

12.

US № 5,770,576

Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity.

Morozov V.G.,
Khavinson V.Kh.

USA, 
23.06.1998

13.

US № 5,789,384

Pharmaceutical dipeptide compositions and methods of use thereof.

Khavinson V.Kh.,
Sery S.V.,
Morozov V.G.

USA, 
04.08.1998

14.

US № 5,807,830

Method for treatment of purulent inflammatory diseases.

Morozov V.G.,
Khavinson V.Kh.

USA, 
15.09.1998

15.

US № 5,811,399

Pharmaceutical dipeptide compositions and methods of use thereof: immunodepressants.

Khavinson V.Kh.,
Morozov V.G.

USA, 
22.09.1998

16.

US № 5,814,611

Pharmaceutical for the therapy of immune deficiency conditions.

Morozov V.G.,
Khavinson V.Kh.

USA, 
29.09.1998

17.

US № 6,066,622

Immunomodulating peptides and methods of use.

Green L.R., Sinackevich N.V., Ivanov V.T., Mikhalyova I.I., Vaskovsky B.V., Mikhaltsov A.N., Khavinson V.Kh., Morozov V.G.

USA, 
23.05.2000

18.

US № 6,100,380

Immunomodulating peptides and methods of use.

Green L.R., Sinackevich N.V., Ivanov V.T., 
Mikhalyova I.I., Vaskovsky B.V., Mikhaltsov A.N., Morozov V.G.,
Khavinson V.Kh.

USA, 
08.08.2000

19.

US № 6,136,788

Pharmaceutical preparation for the therapy of immune deficiency conditions.

Morozov V.G.,
Khavinson V.Kh.

USA, 
24.10.2000

20.

US № 6,139,862

Pharmaceutical dipeptide compositions and methods of use thereof.

Khavinson V.Kh.,
Sery S.V.,
Morozov V.G.

USA, 
31.10.2000

21.

US № 6,346,514

Pharmaceutical lysine-containing polypeptide compositions and method of use thereof.

Green L.R., Sinackevich N.V., Ivanov V.T., 
Mikhalyova I.I., Vaskovsky B.V., Mikhaltsov A.N., Khavinson V.Kh.,
Morozov V.G.

USA, 
12.02.2002

22.

US № 6,368,788

Method of treating complications in immunodepressed states resulting from HIV infection.

Kozhemyakin A.L., Sinackevich N.V., Seryi S.V., 
Rakhilov A.M., Morozov V.G.,
Khavinson V.Kh.

USA,
09.04.2002

23.

СH № 692477 A5

Zusammensetzung zur Stimulation von Wiederherstellungsvorgдngen, enthaltend L-Lysil-L-Glutaminsдure.
(Application of dipeptide L-Lys-L-Glu for stimulation of reparative processes)

Khavinson V.Kh.,
Morozov V.G., 
Malinin V.V., 
Sery S.V.

Switzerland and Liechtenstein, 15.07.2002

24.

EP № 1224212

Tetrapeptide stimulating functional activity of neurones, pharmacological agent based thereon and method of use thereof.

Khavinson V.Kh.,
Morozov V.G., 
Malinin V.V., 
Grigoriev E.I.

European patent,
09.07.2003

25.

ЕР № 1089753

Use of a dipeptide for stimulating repair processes.

Khavinson V.Kh.,
Morozov V.G., 
Malinin V.V., 
Sery S.V.

European patent,
23.07.2003

26.

US № 6,642,201

Use of a dipeptide for stimulating repair processes.

Khavinson V.Kh.,
Morozov V.G., 
Malinin V.V., 
Sery S.V.

USA,
04.11.2003

27.

US № 6,727,227

Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.

Khavinson V.Kh.

USA,
27.04.2004

28.

ЕР № 1325026

Tetrapeptide stimulating functional activity of hepatocytes and its therapeutical use.

Khavinson V.Kh.

European patent,
18.08.2004

29.

ЕР № 1353939

Tetrapeptide regulating prostate functions and its compositions and uses.

Khavinson V.Kh.,
Malinin V.V., 
Grigoriev E.I.

European patent,
25.08.2004

30.

AU № 769847

Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.

Khavinson V.Kh.

Australia,
20.05.2004

31.

AU № 776693

Use of a dipeptide for stimulating repair processes.

Khavinson V.Kh.,
Morozov V.G., 
Malinin V.V., 
Sery S.V.

Australia, 
06.01.2005

32.

ЕР 1179008

Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.

Khavinson V.Kh.

European patent,
22.03.2006

33.

AU № 784578

Tetrapeptide stimulating functional activity of neurones, pharmacological agent based thereon and method of use thereof.

Khavinson V.Kh.,
Morozov V.G., 
Malinin V.V., 
Grigoriev E.I.

Australia,

17.08.2006

34.

US № 7,101,854

Tetrapeptide stimulating the functional activity of hepatocytes, pharmacological substance on its basis and the method of its application.

Khavinson V.Kh.

USA,
05.09.2006

35.

JP 3902406

Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.

Khavinson V.Kh.

Japan,
12.01.2007

36.

US 7,189,701

Tetrapeptide stimulating functional activity of neurons, pharmacological agent based thereon and method of use thereof.

Khavinson V.Kh.,
Morozov V.G., 
Malinin V.V., 
Grigoriev E.I.

USA,
13.03.2007

37.

СА 2,373,128

Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.

Khavinson V.Kh.

Canada,
13.03.2007

38.

ЕА 008541

Tetrapeptide regulating glucose level in case of diabetes mellitus.

Khavinson V.Kh.,
Malinin V.V., 
Grigoriev E.I.,
Ryzhak G.A.

Eurasia,
29.06.2007

39.

IL 146432

Tetrapeptide revealing geroprotective effect, pharmacological substance on its basis, and the method of its application.

Khavinson V.Kh.

Israel,
04.09.2007

40.

ЕР 1758922

Peptide substance restoring function of respiratory organs.

Khavinson V.Kh., Ryzhak G.A., Grigoriev E.I., Ryadnova I.Yu.

European patent,
13.02.2008

41.

ЕР 1758923

Peptide substance restoring myocardium function.

Khavinson V.Kh., Ryzhak G.A., Grigoriev E.I., Ryadnova I.Yu.

European patent,
13.02.2008

42.

ЕА 010156

Peptide stimulating liver tissue regeneration, pharmacological substance based thereon and method of its application.

Khavinson V.Kh.,
Grigoriev E.I., Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.06.2008

43.

ЕА 010157

Peptide stimulating neurones regeneration, pharmacological substance based thereon and method of its application.

Khavinson V.Kh.,
Grigoriev E.I., Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.06.2008

44.

ЕА 010158

Peptide enhancing capillary resistancy, pharmacological substance based thereon and method of its application.

Khavinson V.Kh.,
Grigoriev E.I., Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.06.2008

45.

ЕА 010573

Gepatoprotective substance and method for producing the same.

Khavinson V.Kh.,
Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.10.2008

46.

ЕА 010574

Peptide normalizing osseous and cartilaginous tissue metabolism, pharmacological substance based thereon and method of its application.

Khavinson V.Kh.,
Grigoriev E.I., Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.10.2008

47.

ЕА 010575

Peptide revealing immuno geroprotective effect, pharmacological substance based thereon and method of its application.

Khavinson V.Kh.,
Grigoriev E.I., Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.10.2008

48.

ЕА 010720

Method for obtaining the substance revealing tissue specific activity for supporting therapy, pharmacological substance produced thereby.

Khavinson V.Kh.,
Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.10.2008

49.

ЕА 010722

Pharmaceutical substance normalizing urinary bladder tonus and method for producing the same.

Khavinson V.Kh.,
Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.10.2008

50.

ЕА 010723

Pharmaceutical substance normalizing kidneys functions and method for producing the same.

Khavinson V.Kh.,
Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.10.2008

51.

ЕА 010724

Pharmaceutical substance normalizing cartilaginous tissue functions and method for producing the same.

Khavinson V.Kh.,
Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.10.2008

52.

ЕА 010734

Pharmaceutical substance normalizing blood vessels functions and method for producing the same.

Khavinson V.Kh.,
Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.10.2008

53.

ЕА 010735

Pharmaceutical substance normalizing male reproductive function and method for producing the same.

Khavinson V.Kh.,
Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.10.2008

54.

ЕА 010736

Pharmaceutical substance normalizing female reproductive function and method for producing the same.

Khavinson V.Kh.,
Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.10.2008

55.

ЕА 010737

Pharmaceutical substance revealing geroprotective activity and method for producing the same.

Khavinson V.Kh.,
Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.10.2008

56.

ЕА 010738

Pharmaceutical substance normalizing thyroid gland functions and method for producing the same.

Khavinson V.Kh.,
Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.10.2008

57.

ЕА 010739

Pharmaceutical substance normalizing brain functions and method for producing the same.

Khavinson V.Kh.,
Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.10.2008

58.

ЕА 011092

Peptide revealing stress protective effect, pharmacological substance based thereon and method of its application.

Khavinson V.Kh.,
Grigoriev E.I., Malinin V.V., 
Ryzhak G.A.

Eurasia,
30.12.2008

59.

US 7,491,703

Tetrapeptide regulating blood glucose level in diabetes mellitus.

Khavinson V.Kh.,
Malinin V.V., Grigoriev E.I., 
Ryzhak G.A.

USA,
17.02.2009

60.

ЕР 2024388

Peptide substance stimulating regeneration of central nervous system neurons, pharmaceutical composition on its base, and the method of its application.

Khavinson V.Kh.,

Grigoriev E.I., Malinin V.V.,

Ryzhak G.A.

European patent,
14.10.2009

61.

ЕР 2024387

Peptide substance enhancing capillaries resistance, pharmaceutical composition on its base and the method of its application.

Khavinson V.Kh.,Grigoriev E.I., Malinin V.V., Ryzhak G.A.

European patent,
21.10.2009

62.

US 7,625,870

Peptide substance restoring respiratory organs function.

Khavinson V.Kh., Ryzhak G.A., Grigoriev E.I., Ryadnova I.Yu.

USA,
01.12.2009

63.

ЕР 1697401

Tetrapeptide regulating blood glucose level in diabetes mellitus.

Khavinson V.Kh., Malinin V.V., Grigoriev E.I., Ryzhak G.A.

European patent,
06.01.2010

64.

US 7,662,789

Peptide substance restoring myocardium function.

Khavinson V.Kh., Ryzhak G.A., Grigoriev E.I., Ryadnova I.Yu.

USA,
16.02.2010

65.

JP 4489946

Use of a dipeptide for stimulating repair processes.

Khavinson V.Kh., Morozov V.G.,

Malinin V.V.,

Sery S.V.

Japan,                       09.04.2010